Formulation and Evaluation of Fast Dissolving Tablets of Ondansetron by Solid Dispersion in Superdisintegrants

Formulation and Evaluation of Fast Dissolving Tablets of Amoxicillin Trihydrate Using Synthetic Superdisintegrants

In present study, the fast dissolving tablets of Amoxicillin Trihydrate were prepared by direct compression technique using microcrystalline cellulose (MCC) as direct compressible diluents. Sodium starch glycolate (SSG) and croscarmillose sodium (CCS) used as synthetic superdisintegrants. The swelling indices of the superdisintegrants were also compared. Among both the superdisintegrants, crosc...

Effects of superdisintegrants in oral dissolving formulation of cinitapride tablets.

The initiation of newer techniques and development of mouth dissolving (MD) products has created new avenues of higher patients' compliance. MD formulations are actually lessen the difficulties associated with solid swallowing with better bioavailability of especially poorly soluble drugs. In the current study mouth dissolving tablet (MDT) formulations of cinitapride (1 mg) were prepared by dir...

In Vitro-in Vivo Evaluation of Fast-dissolving Tablets Containing Solid Dispersion of Oxcarbazepine

Objective: Investigation of in vitro/in vivo behaviour of fast-dissolving tablets containing solid dispersions of oxcarbazepine is the focus of the present research work. Methods: The effect of various hydrophilic polymers on the aqueous solubility of oxcarbazepine was studied. Polyethylene glycol 6000 carrier was selected and solid dispersions were prepared by various methods. A total of nine ...

Formulation and Evaluation of orally disintegrating tablets of Ondansetron Hydrochloride using Natural Superdisintegrants

Purpose: To develop orally disintegrating tablets of ondansetron HCl using natural Superdisintegrants. Method: Tablets containing the drug were prepared by dry granulation method using different concentrations of superdisintegrants such as modified gum karaya, modified natural agar, crosscarmellose sodium and sodium starch glycollate. The formulations were evaluated for weight variation, hardne...

formulation and evaluation of domperidone fast disintegrating tablets and its taste masking using solid dispersion technology